The domain within your query sequence starts at position 1616 and ends at position 1726; the E-value for the RPT_1 domain shown below is 7.66e-6.

ALDEENKPGGQQDKTSEQKGRDLDKKDTAVELGKGPEPKGKDLYLEDQGLAEKDKALEQR
GAALQQTQAPEPRARAQEHRDLEQKDEHLELRDKTPEEKDKVLVLEDRAPE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.