The domain within your query sequence starts at position 1646 and ends at position 1752; the E-value for the RPT_1 domain shown below is 5.31e-5.

ELLLDRRLHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAA
SLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.