The domain within your query sequence starts at position 1699 and ends at position 1843; the E-value for the RPT_1 domain shown below is 1.32e-7.

LSKRQSQTSLQFQSPGTTTIVPTNANTNKPPAELSPSASPGKIVNISNVTSMPNQHMSPS
LVKSTLGNNSIAGGSAIHTCSPPSNITSLAGAPFSEPCIQQKIVINTSTPLAPGTQIMMN
GARFIVPPQGLGAGSHVLLISTNPK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.