The domain within your query sequence starts at position 172 and ends at position 240; the E-value for the RPT_1 domain shown below is 2.42e-18.

TQFDPDKQVKEEISRHYYQDRREKEDKIKLLSHDQQGQEERITHFEQKKHVKRNTKLYRN
KRVKKKMIR

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.