The domain within your query sequence starts at position 185 and ends at position 276; the E-value for the RPT_1 domain shown below is 1.77e-12.

NGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAKGSET
PGATPGSKIWDPTPSHTPAGAATPGRGDTPGH

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.