The domain within your query sequence starts at position 194 and ends at position 371; the E-value for the RPT_1 domain shown below is 2.07e-48.

PEGREREGAQESLLPQEEAGSTGMDTSSPSDLPSFCRESQPFQVAQPRGAGQQEAPTQAG
NAGSLEPLLDQLLDEVQVEEPAPAPLNLDGDPGGRVHEGSQKSFWPQEEAGSTGMDTSSP
SDSNSFCRESFPSQVAQPCGSGQEDARTQADSTGPLELLLLDQLLDEVQKEEHVPVPL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.