The domain within your query sequence starts at position 204 and ends at position 327; the E-value for the RPT_1 domain shown below is 9.24e-7.

NIRTEDLDDIIRVAAALQKTDKGEELDNLIRMNKSLNRNQGLDGLFRANLKAQQLDKRAQ
SLESLIYMNTQTDRDGKGNQAFGSLKKINQRADPDRRSQDLRSVIRTHATAERIGRRKQD
LDGL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.