The domain within your query sequence starts at position 209 and ends at position 379; the E-value for the RPT_1 domain shown below is 1.33e-7.

AAILAINDAVERGVVEDTLVTLQNPNALLGNLREPLAAVYQELLALAKMEKAANARNHDD
GQEQDIYESCLTQAEIQGHINLANVQGALEVVDDALERQNPGALLEALHDPVLALQGVRG
TFADWYLEQLTSDREQKSQELGLVRLLEKEEIQAGVAVANEKGDEEQTMLQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.