The domain within your query sequence starts at position 215 and ends at position 305; the E-value for the RPT_1 domain shown below is 2.97e-19.

NSKKMQESCQAECGDDIKMKKSRELEPKGHFREMEDNYMEAQAHEYREMVDSRPRHKMLE
QTLPLENFWAHPGPYNDSRALEEQLPHNLPA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.