The domain within your query sequence starts at position 22 and ends at position 215; the E-value for the RPT_1 domain shown below is 2.35e-7.

IGSEDIVVGCGGFVKSDVEINYSLIEIKLYTKHGTLKYQTDCAPNNGYFMIPLYDKGDFI
LKIEPPLGWSFEPTNVELRVDGVSDICTKGGDINFLFTGFSVNGKVLSKGQPLGPAGVQV
SLRSTGADSKIQSTVTQPGGKFAFFKVLPGDYEILATHPTWALKEASTTVRVTNSNANAA
GPLIVAGYNVSGSV

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.