The domain within your query sequence starts at position 223 and ends at position 300; the E-value for the RPT_1 domain shown below is 2.94e-9.

MDEVQNRIKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGG
QDSLLYPARREQPLKSDQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.