The domain within your query sequence starts at position 247 and ends at position 434; the E-value for the RPT_1 domain shown below is 6.82e-6.

QTMPLDTNQIPYGGQMTIQTDDLTYGTPPNSYQTFYGSQMATPSADQTVYGYQKMPLSEN
QALHRSQKTTPSDEPTFYGNQMTPSDGNQSLYGGQRTTYNRNQTYEGQTMIPSSNVSYYR
AQGTGVQTLCGSQKTTSNDDQTFYGYHMTSPDGNLTFYGGQTTTPNGDQIFYDMQMTTPS
GDQTYNTG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.