The domain within your query sequence starts at position 255 and ends at position 352; the E-value for the RPT_1 domain shown below is 8.15e-5.

PELTTKEARHSFDTKDGLVPCSPRFKEDNKRMEENTDAVDELGSQTASKHKEKELEICAD
GNSEVDACPECYSKTSFAHRPSNSEPIEEEDEPSLSTK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.