The domain within your query sequence starts at position 256 and ends at position 312; the E-value for the RPT_1 domain shown below is 1.6e-14.

PIPITKPVPLTKHMPVTKLVTVSKPVPLTKPVPVSRPIVVSKPVPVSRPIAISRHIP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.