The domain within your query sequence starts at position 294 and ends at position 356; the E-value for the RPT_1 domain shown below is 6.76e-13.

SREKPFEDFLPSHYNYLQFAYYNIGNYTQAIECAKTYLLFFPNDEVMHQNLAYYTAMLGE
EEA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.