The domain within your query sequence starts at position 322 and ends at position 432; the E-value for the RPT_1 domain shown below is 6.53e-5.

LYSSEVWRKRPGDLRLHQHNPELPFAFLLYPFNPQEVLDRFEMPWRNMKQNEHPKASETA
MPTASPLPISLTECQRVNPTGDLSQVKTLCQTTVQKENLQIYELPISAPCQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.