The domain within your query sequence starts at position 346 and ends at position 436; the E-value for the RPT_1 domain shown below is 4.18e-7.

TVSEGVSTKTHQEAVEPEFISHETYKEFTVPIVSSQKTIQESPEPEQYSPETCQPIPGPE
NYSLETCHEMSGPEDLSIKTCQDREEPKHSL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.