The domain within your query sequence starts at position 349 and ends at position 431; the E-value for the RPT_1 domain shown below is 1.22e-8.

DTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSP
PQVTTATLVSSSPPQVTSETPAS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.