The domain within your query sequence starts at position 351 and ends at position 439; the E-value for the RPT_1 domain shown below is 1.82e-5.

KSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPADGTTITESSNLSEIESRL
PKAKLITLCKHESILKWMCNCDHGMYQAL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.