The domain within your query sequence starts at position 390 and ends at position 462; the E-value for the RPT_1 domain shown below is 1.3e-5.

AWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQEGTVEGC
LEQRIEENLPVGC

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.