The domain within your query sequence starts at position 415 and ends at position 501; the E-value for the RPT_1 domain shown below is 1.61e-12.

TKELLLKIIQSSIQSSSVDLGTKELLLKIIQSSIQSSTVDLGTKELLLKIIQSSIQSSSV
DLGTKELLLKIIQSSIQSSTVDLGTKE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.