The domain within your query sequence starts at position 443 and ends at position 588; the E-value for the RPT_1 domain shown below is 1.25e-6.

YDAIRACIGNTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIE
KSNLNRQFLFRPHHIQKPKSYTAAEATLKINPQLKIDAHLNKVCPATESIYSDEFYTKQD
IIITALDNVEARRYVDSRCLANLRPL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.