The domain within your query sequence starts at position 45 and ends at position 218; the E-value for the RPT_1 domain shown below is 6.82e-6.

ETLPIDQVIFTASSQLTNVNDSSRPLLPGYQKTAASRNKVTISNEENQITTLDDNRLATL
NQGPVVNFNADQTSIENCPVISGGDQASSWGQMVTFNADQTHHGHQKMTFSSDQNVNRSQ
VTTSSSDQTMYRDQRTTYSAQNIYRDSMKILSDCYTYYNDQITVPNRNQTFYRG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.