The domain within your query sequence starts at position 461 and ends at position 526; the E-value for the RPT_1 domain shown below is 7.6e-5.

IPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEE
LHLTGN

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.