The domain within your query sequence starts at position 468 and ends at position 645; the E-value for the RPT_1 domain shown below is 2.07e-48.

PGGRVHEGSWESFWPQREAGSTGLDTSSPSDSNSFCRESQTSQVAQPCGSGQEDARTQAN
STGPLELLLLDQLLDEVQKEEHVPAPLDWGRNPGSREHEGSQDSLLPLEEAANSGMDTSI
PSIWPTFCRESQPPQVAQPSGPGKAQAPTQGGNTDPLELFLDQLLTEVQLEEQGPSPV

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.