The domain within your query sequence starts at position 478 and ends at position 616; the E-value for the RPT_1 domain shown below is 1.55e-9.

KRTSFTDQKPMEDNLHSILTSPSTRRTSVSDQRMFYEPIQIKSAPPIIKKTSFAEEKSFQ
QLMEAIMPPQYVKKTSISDQRSSQESLETRRSSHHSQNNMKVFVKTSTTLPPQQRGIQNT
SNHKYDKGSSRTSHHSHDR

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.