The domain within your query sequence starts at position 484 and ends at position 538; the E-value for the RPT_1 domain shown below is 1.81e-8.

GHMGPHCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCICHLSPYGSIYGPYCQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.