The domain within your query sequence starts at position 617 and ends at position 755; the E-value for the RPT_1 domain shown below is 7.57e-6.

SISSEPKASDKYEALREEVSPSPLSSSTVEGAQHPPAAATKYDVFKQLSLEGAGLAMEEF
KENTSSTKSEDDFADFHSSKFSSTSSDKSLGEKAVAFRHAKEDSSSVKSLDLPSIGGSSV
GKEDSEDALSVQFDMKLAD

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.