The domain within your query sequence starts at position 622 and ends at position 738; the E-value for the RPT_1 domain shown below is 6.53e-5.

LESKALWETKEQKKHLWTSDSSCPHKTPLAPFIGPKRINTVDDVPRSEATGKNTDNTKKC
SSSEPPFLNLNPSPALVQQPLRVSPIENPLKSKAWCGHIQRKNNFLASELPAQSLSQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.