The domain within your query sequence starts at position 78 and ends at position 336; the E-value for the RPT_1 domain shown below is 3.02e-14.

VTFGRVTPSRARIFHEQKILQKVFGEWREEWWVSQREWKLCVRADCHYRYYLYNLIFQNW
KTFVHQQREMRKRFRIAEHHDTKQKMCQAWKSWLIYMVSRRTKLHMKTTALEFRRQSVLC
FWWSKWRWRLGQAHAEHALHAVAVKHRALSLQLQGWLRWQEQLLISQRDRRKEATAVQHY
QHWQKQRSLKAWLKYLQICRVKRWQNEMAVQFHRATVLQIHFCDWQWAWEWRQSLSAHQA
LVVKLAGRMVLRRAFTHWK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.