The domain within your query sequence starts at position 98 and ends at position 304; the E-value for the RPT_1 domain shown below is 1.57e-6.

QQKEFSITDCNHERKHANDQTVIFSDENQMDLTASHTVMITKGLSDCTKNENSTKIDTTS
FLENLKHHAANSRIKKDLACSTVSLSQNIFSEKINSDNFIKRLKTGKHISSSTELDKENA
EIPVYSKDSNSASSTYQMHASLGVDENSSNRTRIFREQDDGMNLTQCHTACIKTWIPPST
EAKIGEFKGDKTIYGNECMELTTNYTI

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.