The domain within your query sequence starts at position 1198 and ends at position 1400; the E-value for the RPT_2 domain shown below is 2.22e-8.

QEQAQPSQQGLFQPQVALGSLPPNPMPQNQQGPIFQTQRPIVGMQSNSPSQEQQQQQQQQ
QQQQQQQQQQQQSILFSNQNAMATMASQKQPPPNMMFSPNQNPMASQEQQNQSIFHQQSN
MAPMNQEQQPMQFQNQPTVSSLQNPGPTQSESPQTSLFHSSPQIQLVQGSPSSQDQQVTL
FLSPASMSALQTSINQPDMQQSP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.