The domain within your query sequence starts at position 1298 and ends at position 1417; the E-value for the RPT_2 domain shown below is 2.36e-9.

TTPELQPFTSKKQPAPKPTALVTQGRTYKPSTEDCESVGPVAPDFEPSTSTDHLVTPKVT
DQSLTLQSSPLSASPVSSTPDLKPPVPIAQPVTPEPIPQANHQRKRRAAGKQGSRTVPLG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.