The domain within your query sequence starts at position 140 and ends at position 219; the E-value for the RPT_2 domain shown below is 8.6e-5.

HSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQ
HGHSDRYHLTHTERVLPSHS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.