The domain within your query sequence starts at position 1409 and ends at position 1581; the E-value for the RPT_2 domain shown below is 6.62e-6.

TPSRHSLSGSSPGMKDTPQTPSRGRSECDSSPEPKALPQTPRARSHSPSSPERNNKSVTP
QRERSGSESSVEQKNLARTSPGQRSRSGSSQELDGKPSASPQERSESDSSPDSKPKTRTP
LRQRSHSGSSPEVDSKSRHSPRLSRSGSSPEMKDKPRVLQRAQSGTDSSPEHK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.