The domain within your query sequence starts at position 143 and ends at position 245; the E-value for the RPT_2 domain shown below is 2.25e-8.

AAAFPPQGASIWRNEFGPGPLLPMKRRGAETERHMIPGNGPPLAMCHQPAPPELFETLCF
PIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSD

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.