The domain within your query sequence starts at position 1611 and ends at position 1703; the E-value for the RPT_2 domain shown below is 2.12e-5.

SDSSTAPSVPQDASGSSVPTHMDPKDQNSSVPREALAAPMQSGPGSFTVGSPAQLRGARD
SGSPHKRPGQQDNSSPAKTVGRFSVVSTQDEWT

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.