The domain within your query sequence starts at position 1812 and ends at position 1967; the E-value for the RPT_2 domain shown below is 9.98e-5.

AGQGAFKGRGCETGQGAAGECQGPRSLGSRGSEFVGGRAGFTGSSSVPGRRDSTIYGDAV
TSKPQEPQNELYSPLGRRDFKSVSGGIQEPGFQRGTGQGEGKESFQESGSWEAELDEVQG
SRASAKFENQGGKDPGWSGQKPGPCGSRHQVQSGTE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.