The domain within your query sequence starts at position 1923 and ends at position 2023; the E-value for the RPT_2 domain shown below is 2.12e-5.

SDSSRGPPTKDPAHASTPPGTKAVQTQQPCSVRASLSTDICSGLASDGGGARGQGSSTSS
LAPGPEPGPQPTLHVQAQVNNSNNKKGTFTDDLHKLVDEWT

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.