The domain within your query sequence starts at position 1962 and ends at position 2148; the E-value for the RPT_2 domain shown below is 3.08e-5.

GPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNENEVV
PVLSEKATDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKNRKVK
DAQQVEPEGQEKPSPAVVRSTDPETAKETKAVSEMSAEIGAMISVSSAEYGSDAKESVTD
YTTPSSS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.