The domain within your query sequence starts at position 1962 and ends at position 2148; the E-value for the RPT_2 domain shown below is 4.39e-5.

ISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNENEVVPV
LSEKATDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKNRKVKDA
QQVEPEGQEKPSPAVVRSTDPETAKETKAVSEMSAEIGAMISVSSAEYGSDAKESVTDYT
TPSSSLP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.