The domain within your query sequence starts at position 266 and ends at position 343; the E-value for the RPT_2 domain shown below is 8.6e-5.

HARRAHNNQSWRSDNNQSWRDLNQSWRGRNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRG
HDNQSQRGHNDQSWRAHN

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.