The domain within your query sequence starts at position 271 and ends at position 353; the E-value for the RPT_2 domain shown below is 1.13e-5.

QWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKVIYQSLEGAVQA
GQLKIPPGYHPLDVEKEWGKLHV

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.