The domain within your query sequence starts at position 305 and ends at position 389; the E-value for the RPT_2 domain shown below is 1.06e-13.

VTAKPPAQQAGLEKTSLQQPGPKSLAQTPGQGKVPPGPAKSPAQQPGTAKLPAQQPGPQT
AAKVPGPTKTPAQLSGPGKTPAQQP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.