The domain within your query sequence starts at position 3097 and ends at position 3144; the E-value for the RPT_2 domain shown below is 3.49e-19.

FGQTEGSFQSSNCGQQGTTSYQSSGFDQQRSGLHQSFPCSNHESTSQE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.