The domain within your query sequence starts at position 448 and ends at position 620; the E-value for the RPT_2 domain shown below is 4.89e-7.

SAAKAEVTEGKGDPQPWKKASLPASEKTDPLASSKAGSASQGKAETVSPGEVDAMTLGKT
VPTSSGKTALVSPGKVDLMTSERAEGIPELQASEKGNPVNSTRVDTGATGSTEPKSGVKV
ITQIPGATSPGKVETPSLQKEQPQLSEKTDPSRKVDPPTTVEPVSLGKADSAS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.