The domain within your query sequence starts at position 449 and ends at position 692; the E-value for the RPT_2 domain shown below is 2.94e-114.

GKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQ
GKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQ
SKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQ
GKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAK
KKSG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.