The domain within your query sequence starts at position 456 and ends at position 672; the E-value for the RPT_2 domain shown below is 1.06e-5.

DPTSLAPPLNPHHSILEAKDRESSESRVSSIFQEEEGQIWELVKKEAATEVKVENSLAQE
IQESGLDTEEIQDSQGPLQMETLEALGDEPLMSLKTQNHETPGKENCNSSIEENSGTVKS
PEKEKQTPLKSLEEKNVEAEKTLENGVLELSKPLGEEEPRMEDQELMSPEHTLETVSFLG
KENQEVVRSSEEQNLESLITFKEESQYPLGGPEAEDQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.