The domain within your query sequence starts at position 1623 and ends at position 1769; the E-value for the RPT_3 domain shown below is 4.92e-5.

NPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAA
VSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLT
LAAVGAASKTLSHPQQMALLDQTKTLA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.