The domain within your query sequence starts at position 1983 and ends at position 2153; the E-value for the RPT_3 domain shown below is 9.16e-5.

GSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNENEVVPVLSEKATDKVPEPKEQRQKQ
PRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPAVVRST
DPETAKETKAVSEMSAEIGAMISVSSAEYGSDAKESVTDYTTPSSSLPNTV

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.